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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44935c398c9fb078d000b85f4507687250ec6e0da960f6c022410f20777bf6e1' 
  AND token = 'pUJKi+cJd0lQrlYMSGiMUk6vXDR4npdn3CV0LWnQ0+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}