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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52558cec78a5a3da7a508ac5cc4df6c65bce9c14be72e7ec0df417ddf369ef0f' 
  AND token = 'c5DU1SJBqmA7ROvN+xuiLNf2BqmkobPD0yjBFkMCh7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}