SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6407a6f8de4ebd7022a462efadfc610543e93eb735109305c36966bc4c8021' 
  AND token = '0ez62rxaZBj+rDCyTfWI14KrS0TODDVrm5qQ1WOiY1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}