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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd7b21e9db3a48f15c36bc9a725feac6b9d0da4eb9c33b33799a33cbbd8d142' 
  AND token = '5Ehpu2K3Kg1aFR1i3nr3mTgt2KkMF7EOYBOykE7Uz/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}