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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fddf7941ce001e1b9014c852f0044fe64603550e761a4d6437570798f04157a8' 
  AND token = '1OEXtzES+73rS3Z4ZY40pkDQjuQh3u2c2OQNUuVrbm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}