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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d336c7e9e77bb5d00e3184d174716c21d7dfd766f571d8981708039acf0b2d' 
  AND token = 'ULi7ER49VcDp+uciOFo1+jd5l6GBWd5lndWty2yz/2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}