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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4a22fe48fb08f5ba07eaad66bfb301f29ba3751f15c3343a5f8e5027acc1d1' 
  AND token = 'jaHMNDwDqqFoonmqO4zwoBu1p/3+pO1uf415kI9k1AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}