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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd220bd500f9408ce1c36028110a6d1cd02bf2d32c69db8711de8a824aa79ee30' 
  AND token = 'Yq4PRnaCbqVMX+YfZLTazqJTcT8cJWseq8fbeyb7znE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}