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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3ab6e312848fbcbd421ca67c1b9bfa8013c63636b402b551eec2ed519185b4b' 
  AND token = 'DeMMKEK6iOLMucXqu6S3cnAeqKbWFI/Qqsb9d/k4gRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}