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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2750f41a112d4a782d2e67802d6a54fd8b86893f571aea2d1a3f01e3c6f395c1' 
  AND token = '/FjWvxY9GM3mGjQuchnBpUSOIE7p80briwj7L7HO0dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}