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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d919ca2410394960f3ad1cd172366e5f8a94c5b679d80693df1207298e5de7' 
  AND token = '4JudTR6VEWg0zO2gxGIPIMFu1sM0T5xd6Tva7jshBQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}