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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3001f84d2a9b7a24a406b7239fab226b2426fb6b145aab5e6892e9fdf396e72' 
  AND token = 'FV0MAvVSGUpldog74bx2PK23um/0gVFBvN5saB2EQig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}