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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8a9b62d6324e4d1d732e5985394f3b728a565e837fce9259d835b8d9a3abee' 
  AND token = 'Ese2fSet7GZ2DohQFOGKyvWLBj3yuPf6/0r2Cxv0qwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}