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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea60e57f608516d1da1eb0f485f664632c105cced16e8146344de6066ef4a568' 
  AND token = 'ZQT4KDEC3vpeaE2UZTh9hUGayPbdjQcfO8tCkU0p3LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}