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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1fddeffcb14968fcb472303bc6acb0d6919f8efdc4681aa7c3822e58e51b416' 
  AND token = '59/Sn6nI3JE7pZ9CaSm4c4wiYzRPZrX84wdG/ox6UL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}