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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3325895bd1b57575d6d60475bc87c0a9b8f7698a06fd861049a08a68211affda' 
  AND token = '6Bq5mUkwgd7FUnH0UvIvAgl8BqCPUf69PR9hNLsDiec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}