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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1f48e7aba0a4d032bd4fe00dcfaef225e87cf24edfaf73b2c7c0808bbab499' 
  AND token = '7lFSqjaecFXREhllo066jgAqIRT3ND/nEvRT3FwOoqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}