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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9ec5cc5fcbde6b2829d105f5aa54a66e819c5018a528178e61488b44cc13a01' 
  AND token = 'CC/aXnAFDDxPh+zrt1p68HZ4/2UPr7pcLYoh++2Yul8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}