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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65fa1cd5be0088c48d7a1332a327f3b44ac3b70f48236d12e4f4e0fe181af333' 
  AND token = 'qV4VVEswt2MtYFjI1XsZuH5skhMU1iVp7ZhZNLqlCuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}