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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b43fd7b578cb2f6f7077e1e9880d45645532489e54f8852a9a132583542953d' 
  AND token = 'N64zAc7CEaNamMmUhViCpB5BSLFC5/q0n5L5ezxPdI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}