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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e216f6436ed1d648e2dbefaea721b9db86506a14249c0877ea91b8e648bca65' 
  AND token = 'lcVbr0KGHjKeSkyGIynC6bDF9XXHr81Ae/LHV6VoeDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}