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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218b002fc16294c7e07dc59cdfbee240e92c0c4bb529769883f900494c467b81' 
  AND token = 'c1RL+7f+AlEvpbO1aca0mAe8KOdEMiGzSa4Yuk3zOlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}