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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101d207988db122c577fa1de012920a06ab590bb5e6eab74635142e937bc4dd1' 
  AND token = 'qUgzN/2o2Se5NtrmBNFp0VtLwTLTsBP9zinsQe3gmtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}