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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595b77eb565f58855ca96ab0367cd29ccc33127be525107c43923f17d3650b1d' 
  AND token = 'J5jYUQUrZAY7fiSkO1mkSvBbz+rSGVR2bxSh6uAQvBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}