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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b376ed5b1e5679d8b73bdee1dc1e38912c8db286d64e7d93e1a29185e8c4a95f' 
  AND token = '4Ibd/CwBwA3eBM4ZWEFoAtG8Q02pW5qbXL/vUcYDKcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}