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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4a5fad86ec86ef54e910636dbed360aa1e10cd2bc8027c30ba971cb974d2087' 
  AND token = 'GfwmSBvjr4XPZifqQ7LdgNx8dfvvZD1Yt8LXmoBPum0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}