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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b8d3552108ba349b8d2e373345f0de3c63bd5ad2af8a17afb844c59c139282' 
  AND token = 'OlIX9bURuKYuDPPr58dUEFTOLbcaxV8mc28e+Th/Di8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}