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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be41f1ae8fa40ca9599f68581f36b02df1e6e8601e659bb4160465c48ccd368' 
  AND token = 'yaKK7PpPV3bnX37dgGvrTXRh/+1Vc9QLUKgVzGctQd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}