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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d444e73c42a66d16b1c6cfecb33ce5d44a43e9a4f6d9406597aa4278d1b4b1' 
  AND token = 'aOGNOancbhSufj2o++xhx5G45t5QrNR2rOsFC6MHeVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}