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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eaab1432010ff0486b72966690a9c2792cebac8799c5ff02b4edf7d8de380d5' 
  AND token = 'v+8rP+kuNp1q2MfvJCWFGgwmw9CSJvTibtmpp2a0Qfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}