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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b10c75dd25bd56ac95a8ce2267eaad4d4eabebee3b0fe37e93d4f8c2e2187fd' 
  AND token = 'wpl/h1uZKvO6n+6lLpDby37cT9EcvU0Y8TPbvfc/iEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}