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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5c8c747bad747930d5f468f4951b78b825e8eeb055684f5de2c6156c92e312' 
  AND token = 't8w2bANgxy+If3PcDapFedlB17TYS3CQeSnQt1eVj98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}