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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d5a2a161f4623129848f7630c3558c730c349049d52af9f44d99802c73df0f' 
  AND token = 'EFrUB4TIK2S3ZfpCsCgo4zHaY7h9hsI0jk0SYn1fvHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}