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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c5eaf677ee830ea2ec9f5de0cf45f983563917d61f7edc3d9cdd644e88781d' 
  AND token = 'WXf01QE42/djE94lHt6rO/rjpPDMDpdEr3ItdupPouk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}