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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66c253d501a485f62a5023607591bd251fa060e8e4de91636c2010de51a0821' 
  AND token = 'zM4RJbKtKW91hAZ1oC/tJB7glWCM0+WS2C6Gy3Nm5zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}