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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd426913d751d7642f6d4f1590b47e558d3bd78fba8e1799551b1b49c200c292a' 
  AND token = 'uO/Fq2SA990q8Ro0Gnsze3RM7cy17NIvb3/Q4U1fKsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}