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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f6e8fa45cb269cdaeb3b6c8d8657797a7ab331cf70ffb432d78bbd76e9df94c' 
  AND token = 'Y6nqxZZmCnAc9q+U8dXSj/NmUN2px35IHbxN1NA6oXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}